Indian scientists conduct first human clinical trial of hemophilia A gene therapy -

Union Science and Technology Minister Jitendra Singh on Wednesday said India has conducted the first human clinical trial of gene therapy for 'Haemophilia A' at the Christian Medical College – Vellore. He further informed that this program will be conducted at the Center for Stem Cell Research, a unit of INSTEM, Bengaluru, Department of Biotechnology (DBT), Emory University at Christian Medical College (CMC), Vellore, United States of America (USA). ) is supported in collaboration with.

He said the trials include deploying a new technology of using a lentiviral vector to express the FVIII transgene in the patient's own hematopoietic stem cells that will then express FVIII from uniquely differentiated blood cells. Addressing the National Science Day celebrations in Delhi, he expressed hope that the manufacturing of this vector will start soon in India and proceed with further clinical trials.

Speaking on India's efforts in advanced technologies, he said, “India is ready to match global standards in quantum technology, artificial intelligence and machine learning. He said that we are not only unanimous but are also ahead of others in some ways. He further said that to increase the effectiveness of AI, we are also using human interface at various levels.

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